4th Annual Biotechnology Lecture and Awards
Session I: Annual Biotechnology Lecture
||Lars Juhl Jensen, Disease Systems Biology, NNF Centre for Protein
Research, University of Copenhagen, Panum Institute: Presentation of 4th
Annual Biotechnology Lecture.
||Bernhard Palsson, Department of Bioengineering, University of California,
San Diego, La Jolla, CA, USA: The meta-structure of the E. coli genome and
its genome-scale transcriptional regulatory network
Regulation of gene expression is widely considered to be a core issue in biology. Normally such studies have focused on a single gene or a group of genes. Advances in ChIP-chip technology now enable us to study this issue on a genome scale. We have obtained close to a 100 ChIP-chip data sets for E. coli K-12 MG1655 that include; RNAP, the sigma factors, most of the broad acting transcription factors (TFs), and the majority of the nucleoid associated protein (NAPs). In addition we have obtained tiling array data for expression profiling and transcription start site (TSS) data from short read sequencing technology. Degradation start sites (DSS) are obtained by a variation of the TSS protocol. This data enables us to 1) formulate the metastrucure (that is comprised of the functional, structural and operational annotation) of the E. coli genome and 2) to draft the reconstruction of the transcriptional regulatory network (TRN) in E. coli at a genome-scale.
Session II: Annual Biotechnology Awards for Young Researchers
||Steen Gammeltoft, Glostrup Hospital, Denmark: Presentation of 4 Annual
Biotechnology Awards for Young Researchers.
|| Dimitrios Stamou, Bio-Nanotechnology Laboratory, Dept. Neuroscience and
Pharmacology and Nano-Science Center, University of Copenhagen: Lipid-
Membrane Biotechnology and Synthetic Biology on the Nanoscale.
||Tina Hummelshøj, Dept. Clinical Immunology, Rigshospitalet: The Ficolins –
new defence players of the innate immune system.
|15:20-15:40||Karl, Agger, BRIC, Biocenter, University of Copenhagen: Erasing the histone
methylation mark: Identification and characterization of histone
||Reception and refreshments|
Registration on-line: www.biokemi.org
Everybody is welcome. Admission is free. Registration is encouraged.
Secretariat: Vivian Juhl, Dept. of Clinical Biochemistry, Glostrup Hospital, 2600 Glostrup, Denmark. Tel: 38 63 24 58. firstname.lastname@example.org