Nano-Science Center > Seminarer og events > Stochastic sensing wit...

Stochastic sensing with ion channels and solid-state nanopores

Stochastic sensing with ion channels and solid-state nanopores

Abstract
By analyzing the fluctuations in the ionic current through membrane protein channels and artificial nanopores, one can learn not only about the interactions between small ions and the pore, but also on the transport of larger molecules. Transient occlusions of the channel by these molecules report on their penetration into, and dynamic within the channel. I will present our recent progress on (i) the real-time detection of single-proton binding in the nicotinic acetylcholine receptor channel, (ii) the translocation of antibiotics through the bacterial channel OmpF, (iii) the fabrication and electrical characterization of silicon-based nanopores.